Changes in your TOE are the first sign of brutal B12 deficiency that leaves one in 10 women 'tired all the time', say experts

A tingling or numb feeling in your toes may seem like a minor annoyance, but health experts say it could be one of the earliest signs of vitamin B12 deficiency—a condition that can affect energy levels, nerve function, and overall health.

Vitamin B12 plays a vital role in producing healthy red blood cells and maintaining the protective covering around nerves. When levels become too low, the body's longest nerves—particularly those extending to the feet and toes—are often affected first.

According to foot health experts, symptoms can include tingling, numbness, burning sensations, cold feet, changes in skin color, and slow-healing wounds. Many people also experience persistent fatigue, brain fog, poor concentration, low mood, or weakness, symptoms that are sometimes mistaken for stress or aging.

Older adults are at higher risk because the body's ability to absorb vitamin B12 naturally decreases with age. People who follow strict vegan diets or have certain digestive conditions may also be more likely to develop a deficiency.

Doctors say anyone experiencing ongoing numbness, tingling, or unexplained tiredness should seek medical advice rather than ignoring the symptoms. A simple blood test can help determine whether vitamin B12 deficiency or another condition—such as diabetes—is responsible.

Early diagnosis is important because untreated vitamin B12 deficiency can lead to permanent nerve damage and other serious health complications. If caught in time, treatment with vitamin B12 supplements or injections is often highly effective.